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TOX Rat anti-Human, Mouse, PE, Clone: TXRX10, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-6502-82

Additional Details : Weight : 0.25000kg

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Product Code. 15209259

  • 2420.00 SEK / 100µg


In stock, ready to ship: 6
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Description

Description

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
Specifications

Specifications

TOX
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q66JW3, O94900
TOX1, thymocyte selection-associated high mobility group box protein TOX, thymus high mobility group box protein TOX
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Flow Cytometry
TXRX10
PE
TOX
Liquid
Tox
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
252838, 9760
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For Research Use Only.