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  6. Invitrogen™ Transferrin Receptor Monoclonal Antibody (H68.4) 

Invitrogen™ Transferrin Receptor Monoclonal Antibody (H68.4)
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Produktkod. 10372703
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100 μg
500 μg
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Varje
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10372703 100 μg Varje
10516083 500 μg Varje
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For Research Use Only. All usage must comply with product instructions.
Produktkod. 10372703 Leverantör Invitrogen™ Leverantörsnummer 136800

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For Research Use Only. All usage must comply with product instructions.

Beskrivning

Mouse Monoclonal Antibody

H68.4 is specific to residues 3-28 of the human transferrin receptor (TfR) tail.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Transferrin Receptor
Användningsområden ELISA, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassificering Monoclonal
Klona H68.4
Koncentration 0.5 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.1% sodium azide; pH 7.4
Gen TFRC
Genaccessionsnr. P02786, Q07891, Q62351, Q90997, Q99376
Gene Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gensymboler TFRC
Värd art Mouse
Immunogen Recombinant human transferrin receptor.
Reningsmetod Affinity chromatography
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 100689395, 22042, 396191, 64678, 7037
Målarter Human, Mouse, Rat, Hamster, Chicken
Innehåll och lagring -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG1
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