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Invitrogen™ TRF2 Monoclonal Antibody (3H6B4)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA531925
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Beskrivning
MA5-31925 has been tested in indirect ELISA.
TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.
Specifikationer
| TRF2 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| Q15554 | |
| TERF2 | |
| Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 3H6B4 | |
| Unconjugated | |
| TERF2 | |
| Telomeric DNA-binding protein; telomeric repeat binding factor 2; telomeric repeat binding protein 2; telomeric repeat-binding factor 2; TERF2; TRBF2; TRF2; TTAGGG repeat-binding factor 2 | |
| Mouse | |
| Protein G | |
| RUO | |
| 7014 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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