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TRIB3 Mouse anti-Human, Mouse, Rat, Clone: 2C10C7, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66702-1-IG-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16878825

  • 4721.67 SEK / 150µL
Estimated Shipment: 03-04-2024
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Description

Description

A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.
Specifications

Specifications

TRIB3
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8K4K2, Q96RU7, Q9WTQ6
TRIB3
TRIB3 Fusion Protein Ag25776
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG1
Western Blot
2C10C7
Unconjugated
TRIB3
C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3
Mouse
Protein G
RUO
228775, 246273, 57761
-20°C
Liquid
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