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TXNRD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11117-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionThis gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
|GRIM 12, GRIM12, KDRF, thioredoxin reductase 1, Thioredoxin reductase TR1, TR, TR1, TRXR1, TXNR, TXNRD1|
|Antigen Affinity Chromatography|
|50493, 58819, 7296|
|Flow Cytometry, Immunoprecipitation, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|O89049, Q16881, Q9JMH6|
|TXNRD1 Fusion Protein Ag1618|
|Mouse, Human, Rat|