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TYMS Mouse anti-Human, Clone: 1F5B7, Proteintech
Mouse Monoclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
| Antigen | TYMS |
|---|---|
| Clone | 1F5B7 |
| Concentration | 1 mg/mL |
| Applications | Western Blot, Immunohistochemistry (Paraffin) |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16828875
|
Proteintech
66725-1-IG-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 19-04-2024 Log in to see stock. |
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|
16818875
|
Proteintech
66725-1-IG-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 19-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Thymidylate Synthase (TS) (EC 2.1.1.45) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.Specifications
| TYMS | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| HsT422, Thymidylate synthase, thymidylate synthetase, TMS, TS, TSase, TYMS | |
| TYMS | |
| IgG1 | |
| Protein G | |
| Antibody |
| 1F5B7 | |
| Western Blot, Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Mouse | |
| Human | |
| P04818 | |
| 7298 | |
| TYMS Fusion Protein Ag7027 | |
| Primary | |
| -20°C | |
| TYMS |