missing translation for 'onlineSavingsMsg'
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Invitrogen™ Human ULK1, GST Tag Recombinant Protein
ULK1 is a serine/threonine protein kinase that plays critical role during initial stages of autophagy which is a vital response to nutrient starvation. Recombinant human ULK1 (1-649) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
4165.00 SEK - 64700.00 SEK
Specifications
| Gene Alias | ATG1, UNC51, Unc51.1, FLJ38455 |
|---|---|
| Protein Length | aa 1-649 |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | GST Tag |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15431234
|
Invitrogen™
PV6430 |
10μg |
4165.00 SEK
10µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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|
15409053
|
Invitrogen™
PV6431 |
100μg |
14440.00 SEK
100µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
15419053
|
Invitrogen™
PV6432 |
1mg |
64700.00 SEK
1mg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The conserved C-terminal domain (CTD) of ULK1 controls the regulatory function and localization of the protein. Knockdown of ULK1 inhibits the autophagic response as well as inhibiting rapamycin-induced autophagy consistent with a role downstream of mTOR. ULK1 forms a complex with FIP200 and ATG13 and this complex is essential for starvation-induced autophagy. Both FIP200 and ATG13 are critical for correct localization of ULK1 to the pre-autophagosome and stability of ULK1 protein. ULK1 is phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Specifications
| ATG1, UNC51, Unc51.1, FLJ38455 | |
| Human | |
| GST Tag |
| aa 1-649 | |
| Recombinant |