missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ Human ULK2, GST Tag Recombinant Protein

Human ULK2, GST Tag Recombinant Protein

Brand:  Invitrogen™ PV6434

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15429053

  • 14440.00 SEK / 100µg
Estimated Shipment: 16-04-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Mammalian Atg13 binds ULK2 and mediates the interaction of the ULK protein with FIP200. The binding of Atg13 stabilizes and activates ULK and facilitates the phosphorylation of FIP200 by ULK. The ULK-Atg13-FIP200 complex is a direct target of mTOR and important regulator of autophagy in response to mTOR signalling. Yeast 2-hybrid assays showed the C-terminus of ULK2 binds the C-terminus of SynGAP, a negative regulator of Ras that is associated with neural development.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
81.3kDa
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
aa 1-478. Contains V370M SNP
Recombinant
50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol
100μg
Unc51.2, KIAA0623
Human
GST Tag
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers