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Invitrogen™ Human ULK2, GST Tag Recombinant Protein

Human ULK2, GST Tag Recombinant Protein

Brand:  Invitrogen™ PV6433

Additional Details : Weight : 0.01000kg

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Product Code. 15441234

  • 4230.00 SEK / 10µg
Estimated Shipment: 16-04-2024
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Description

Description

Mammalian Atg13 binds ULK2 and mediates the interaction of the ULK protein with FIP200. The binding of Atg13 stabilizes and activates ULK and facilitates the phosphorylation of FIP200 by ULK. The ULK-Atg13-FIP200 complex is a direct target of mTOR and important regulator of autophagy in response to mTOR signalling. Yeast 2-hybrid assays showed the C-terminus of ULK2 binds the C-terminus of SynGAP, a negative regulator of Ras that is associated with neural development.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Kinase Assay
10μg
aa 1-478. Contains V370M SNP
Recombinant
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Serine/Threonine Kinase
Baculovirus
Recombinant, Fragment
Serine/Threonine Kinases
81.3 kDa
Unc51.2, KIAA0623
Human
GST Tag
Biochemical binding/kinetic
ULK2
Kinases & Inhibitors
Liquid
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