missing translation for 'onlineSavingsMsg'
Learn More

ULK3 Recombinant Human Protein

ULK3 Recombinant Human Protein

Brand:  Invitrogen PV6436

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15451234

  • 2975.00 SEK / 10µg


Estimated Shipment date
from Supplier 04-01-2018
Add to basket

Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins. Full-length recombinant human ULK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use

    Related Product:
    LanthaScreen™ Eu Kinase Binding Assay
  • Specifications

    Specifications

    NP_001271293.1
    Pharma and biopharma, protein assays and analysis, target and lead identification and validation
    ULK3 Recombinant Human Protein
    10μg
    For research use only. Not for use in diagnostic procedures
    DKFZP434C131
    ULK3 was pre-diluted in enzyme dilution buffer and assayed in 5mM MOPS (pH 7.2), 2.5mM β-glycerol-phosphate, 5mM MgCl2, 0.4mM EDTA, 1mM EGTA, 0.05mM DTT, with 50μM ATP, trace [33P]-γ-ATP and 200μg/mL casein, dephosphorylated, protein substrate for 15 min.s at 30°C
    Amino acids 44-end
    230nmoles of phosphate transferred to Casein, dephosphorylated, protein substrate per minute per mg of total protein at 30°C
    His Tag
    0.1mg/mL
    54.3kDa
    >95% by SDS-PAGE
    –68 to –85°C
    1 Each
    ULK3 Recombinant Human Protein
    Kinase assay
    ULK3 Recombinant Human Protein
    Human
    Videos