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USP5 Mouse anti-Human, Clone: 3F12C10, Proteintech
Mouse Monoclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
| Antigen | USP5 |
|---|---|
| Clone | 3F12C10 |
| Concentration | 0.91 mg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16827885
|
Proteintech
66213-1-IG-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 15-05-2024 Log in to see stock. |
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|
16817885
|
Proteintech
66213-1-IG-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 15-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
USP5 (ubiquitin carboxyl-terminal hydrolase 5) cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. It is involved in uchored Lys-48-linked polyubiquitin disassembly, and also binds linear and Lys-63 linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the uchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.Specifications
| USP5 | |
| 0.91 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5 | |
| USP5 | |
| IgG2a | |
| Protein A | |
| Antibody |
| 3F12C10 | |
| Western Blot | |
| Unconjugated | |
| Mouse | |
| Human | |
| P45974 | |
| 8078 | |
| USP5 Fusion Protein Ag7575 | |
| Primary | |
| -20°C | |
| USP5 |