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Valproic acid, MedChemExpress

Produktkod. 16496757
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16496757 5 g
16462936 25 g
16411069 1 g
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Produktkod. 16496757 Leverantör Medchem Express Leverantörsnummer HY10585

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Descripción

MedChemExpress Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches.

Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches.

Especificaciones

Kemiskt namn eller material Valproic acid
Fysisk form Liquid
CAS 99-66-1
Färg Light Yellow
Kvantitet 5 g
Anteckningar om renhetsgrad Research
Molekylformel C8H16O2
För användning med (applikation) Cancer-Kinase/protease
Synonym VPA 2-Propylpentanoic Acid
Löslighetsinformation DMSO : 100 mg/mL (693.43 mM; Need ultrasonic) ∣H2O : 1 mg/mL (6.93 mM; Need ultrasonic and warming)
LEDER CCCC(CCC)C(O)=O
Molekylvikt (g/mol) 144.21
Formel vikt 144.21
Procent renhet 98.0%
Kvalitet Research
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Research purposes only

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