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Invitrogen™ VEGF Receptor 2 Monoclonal Antibody (4B4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA515556

Produktkod. 11325523

  • 5200.00 SEK / 100µL

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Beskrivning

Beskrivning

MA5-15556 targets KDR in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15556 immunogen is purified recombinant extracellular fragment of human KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells. MA5-15556 detects KDR which has a predicted molecular weight of approximately 152kDa.

KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
TRUSTED_SUSTAINABILITY
Specifikationer

Specifikationer

VEGF Receptor 2
Monoclonal
Conc. Not Determined
Ascites with 0.03% sodium azide
P35968
KDR
Purified recombinant extracellular fragment of human KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.
RUO
3791
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
4B4
Unconjugated
KDR
6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
Mouse
100 μL
Primary
Human
Antibody
IgG1
Produktförslag

Produktförslag

Filmer
SDS
Dokument

Dokument

Certifikat
Kampanjer

Kampanjer

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