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Invitrogen™ Phospho-MYOD (Thr115) Polyclonal Antibody
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Produktkod. 16691795
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Kvantitet:
100 μL
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16691795 100 μL
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Produktkod. 16691795 Leverantör Invitrogen™ Leverantörsnummer PA5105354

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Beskrivning

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of MyoD1 only when phosphorylated at Thr115.

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).
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Specifikationer

Antigen Phospho-MYOD (Thr115)
Användningsområden Western Blot, Immunocytochemistry
Klassificering Polyclonal
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gen MYOD1
Genaccessionsnr. P10085, P15172, Q02346
Gene Alias AI503393; bHLHc1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; myoblast determination protein 1 homolog; Myod; MYOD1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; myogenic factor 3; PUM; unnamed protein product
Gensymboler MYOD1
Värd art Rabbit
Immunogen A synthesized peptide derived from human MYOD1(Accession P15172), corresponding to amino acid residues around phosphorylated Thr115.
Reningsmetod Sequential chromatography
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 17927, 337868, 4654
Målarter Human, Mouse, Rat
Innehåll och lagring -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG
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