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von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody.
1371.90 SEK - 6975.00 SEK
Specifications
| Antigen | von Hippel-Lindau (vHL) Protein Ab-1 |
|---|---|
| Clone | Ig33 |
| Classification | Monoclonal |
| Form | Concentrated |
| Host Species | Mouse |
| Product Code | Brand | Conjugate | Concentration | Quantity | Price | Quantity & Availability | |||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Conjugate | Concentration | Quantity | Price | Quantity & Availability | |||
|
12672037
|
Epredia
MS-690-P1 |
Unconjugated | 200μg/mL | 500 μL |
4865.00 SEK
500µL |
Estimated Shipment: 17-06-2024 Log in to see stock. |
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|
12642037
|
Epredia
MS-690-B1 |
Biotin | 200μg/mL | 500 μL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
||||
|
12662037
|
Epredia
MS-690-P0 |
Unconjugated | 200μg/mL | 100 μL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
||||
|
12632037
|
Epredia
MS-690-B0 |
Biotin | 200μg/mL | 100 μL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
||||
|
12652037
|
Epredia
MS-690-P |
Unconjugated | 200μg/mL | 1 mL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
||||
|
12682037
|
Epredia
MS-690-P1ABX |
Unconjugated | 1mg/mL | 100 μL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
||||
|
12692037
|
Epredia
MS-690-PABX |
Unconjugated | 1mg/mL | 200 μL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Molecular genetic studies suggest that VHL is a tumor-suppressor gene. Alterations in the von Hippel-Lindau (VHL) gene are correlated with a diverse group of neoplasms including hemangioblastoma, clear cell renal carcinoma (RCC), and pheochromocytoma. Two transcriptional elongation factors, Elongin B and C, are shown to bind in vitro and in vivo to a short, colinear region of the VHL protein (pVHL) that is frequently mutated in human tumors. It is proposed that pVHL functions in vivo as a negative regulator of transcription elongation.Host Species: Mouse
Clone: Ig33
Isotype: IgG1/κ
Species Reactivity: Human and Mouse. Others not known.
Epitope: aa 1-54
Immunogen: A recombinant protein containing aa 1-213 of human vHL
Molecular Weight: 30kDa
Positive Control: Kidney
Cellular Localization: Cytoplasmic Ab-1 does not recognize the truncated form of VHL protein.
Note:
USA: RUO; Int'l: RUO
Specifications
| von Hippel-Lindau (vHL) Protein Ab-1 | |
| Monoclonal | |
| Mouse | |
| Cancer and Tumor Biology | |
| A recombinant protein containing aa 1-213 of human VHL | |
| Primary |
| Ig33 | |
| Concentrated | |
| RUO | |
| Human, Mouse | |
| IgG2a κ |