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Tocris Bioscience™ VU 0409551
GREENER_CHOICE

Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable

Brand:  Tocris Bioscience™ 5693/10

Encompass

Product Code. 15747056

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Description

Description

VU 0409551 is a selective mGlu5 positive allosteric modulator (EC50 = 260 nM). Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu5 signaling via Gαq. Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available.
Specifications

Specifications

[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
1363281-27-9
JNJ 46778212
10 mg
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