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  5. Tocris Bioscience™ VU 6019650

Tocris Bioscience™ VU 6019650

Product Code. 30040318
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30040324 10 mg
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Product Code. 30040318 Supplier Tocris Bioscience™ Supplier No. 8055/50

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Description

M5 receptor antagonist

VU 6019650 is a potent and selective M5 receptor antagonist (hM5 IC50 = 36 nM). Exhibits >100-fold selectivity over human and rat M1-4. In vivo, VU 6019650 inhibits the reward effects of oxycodone and reduces oxycodone self-administration in rats. VU 6019650 is blood brain barrier penetrant.
TRUSTED_SUSTAINABILITY

Specifications

Kemiskt namn eller material (3R,4S)-rel-1-[(2,3-Dihydro-5-benzofuranyl)sulfonyl]-3-fluoro-4-[[(1-methyl-1H-imidazol-2-yl)thio]methyl]piperidine
CAS 2926782-31-0
Kvantitet 50 mg
Mål Muscarinic Acetylcholine Receptor M5/CHRM5
Molekylformel C18H22FN3O3S2
Renhet 0.98
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