missing translation for 'onlineSavingsMsg'
Läs mer
  1. Home
  2. Products
  3. Antikroppar
  4. Primära antikroppar
  5. Alla primära antikroppar
  6. 10342463

Invitrogen™ ZO-1 Polyclonal Antibody
GREENER_CHOICE

Produktkod. 10342463
Change view
Klicka för att se tillgängliga alternativ
Kvantitet:
100 μg
Förpackningsstorlek:
100µg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Produktkod. Kvantitet unitSize
10342463 100 μg 100µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denna artikel kan inte returneras. Se returpolicy

For Research Use Only. All usage must comply with product instructions.
Produktkod. 10342463 Leverantör Invitrogen™ Leverantörsnummer 617300

Vänligen för att beställa denna produkten. Behöver du ett Webbkonto? Registrera ditt konto idag!

3990.00 SEK valid until 2026-04-10
BÄSTA PRIS på kampanj! Använd kampanjkod: "27964" för att få ditt kampanjpris.
Denna artikel kan inte returneras. Se returpolicy

For Research Use Only. All usage must comply with product instructions.

Beskrivning

Rabbit Polyclonal Antibody

61-7300 has been successfully used in Western blot, Immunoprecipitation, Immunofluorescence, ELISA and Immunohistochemistry. To achieve appropriate staining results on formalin-fixed, paraffin embedded tissue sections, protease Type XIV (Actinase E) pretreatment is required. The recommended dilution and incubation for protease is 1-2 mg/mL at 37°C for 10 minutes. Other enzyme and Heat Induced Epitope Retrieval pre-treatment methods may not be suitable for this particular antibody. Frozen sections have been successfully stained after fixation with acetone at 4°C.

ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen ZO-1
Användningsområden ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassificering Polyclonal
Koncentration 0.25 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.1% sodium azide; pH 7.4
Gen TJP1
Genaccessionsnr. O97758, P39447, Q07157
Gene Alias DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
Gensymboler TJP1
Värd art Rabbit
Immunogen A 69 kD fusion protein(1) corresponding to amino acids 463-1109 of human ZO-1 cDNA.(2) This sequence lies N-terminal to the 80 amino acid region (the alpha-motif) present in the a+-isoform but absent in the a- isoform due to alternative splicing.
Reningsmetod Antigen affinity chromatography
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 100718142, 21872, 292994, 403752, 7082
Målarter Canine, Guinea Pig, Human, Mouse, Monkey, Rat
Innehåll och lagring -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG
Visa mer Visa mindre
Produkttitel
Välj ett problem

Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.