Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at ′Leu-104′, thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1.
DDI1, DNA-damage inducible 1, homolog 2; DNA-damage inducible 1 homolog 2; DNA-damage inducible protein 2 (DDI2); Protein DDI1 homolog 2
Cat # 16571322
100 µg
Cat # 15758081
100 µL
Cat # 15708121
100 µL
Cat # 13268578
400 µL
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