PDIR (protein disulfide isomerase-related protein) is a novel PDI protein that was originally isolated from a human placental cDNA library. It has been suggested that from its nucleotide sequence, PDIR has three CXXC-like motifs (Cys-Ser-Met-Cys, Cys-Gly-His-Cys and Cys-Pro-His-Cys), which are found in the PDI superfamily of proteins. The CXXC motif is responsible for oxidoreductase activity. PDIR is also shown to have a putative endoplasmic reticulum (ER) retention signal ′Lys-Glu-Glu-Leu′ at its carboxyl terminus, indicative of ER resident proteins. Northern blot analysis of PDIR indicates that it is preferentially expressed in cells actively secreting proteins. It ...
Cat # 11598721
100 µL
Cat # 16874764
20 µL
Cat # 16864764
150 µL
Cat # 13279638
100 µL
Cat # 16577541
100 µL
Cat # 15775226
0.1 ml
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