A collection of genes utilized by the RNA interference (RNAi) pathway; the RNAi pathway is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. Ideal for genetic screening.
The Silencer Human Drug Targets siRNA Library contains 23,745 Invitrogen™ Silencer siRNAs targeting 7,915 genes for performing RNAi screens against known human drug target genes.
The Silencer™ Select Human Ubiquitin siRNA Library contains 2,943 Invitrogen™ Silencer Select siRNA s targeting 981 genes, including ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin ligases.
Targets 475 genes with up to 4 gRNA per gene target for a total of 1,900 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
The Invitrogen™ LentiArray™ Human Cancer Biology Library targets 510 genes commonly involved in the development of cancer with up to 4 gRNA per gene target (pooled in a single well) for a total of 2,040 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
Obtain the benefits of Invitrogen™ Silencer™ Select siRNAs in a convenient pre-plated, library format. These siRNA collections enable medium and high throughput analysis of phenotypes resulting from inhibition of large sets of targets from specific functional classes.
Targets 98 genes with up to 4 gRNA per gene target for a total of 392 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
Targets 1,444 genes with up to 4 gRNA per gene target for a total of 5,776 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
The Silencer™ Select Human Drug Transporter siRNA Library provides investigators with a focused RNAi screening platform targeting the most up-to-date transporter genes important in entry and extrusion of drugs into and out of cells.
The Silencer™ Human Kinase siRNA Library contains 2,127 Invitrogen™ Silencer siRNAs targeting 709 human kinase genes for performing RNAi screens against the kinome.