CAS RN 1073160-26-5

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Defactinib hydrochloride, MedChemExpress

MedChemExpress Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

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Specifications

Molecular Weight (g/mol)	546.95
Color	Off-White
Physical Form	Powder
Chemical Name or Material	Defactinib hydrochloride
Grade	Research
SMILES	O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1.[H]Cl
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.03%
CAS	1073160-26-5
Solubility Information	DMSO : 30 mg/mL (54.85 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Synonym	VS-6063 hydrochloride PF 04554878 hydrochloride
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₀H₂₂ClF₃N₈O₃S
Formula Weight	546.95

CAS RN 1073160-26-5

CAS RN 1073160-26-5

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