CAS RN 1109276-89-2

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Potent and selective DGAT-1 inhibitor; orally bioavailable

CAS	1109276-89-2
Chemical Name or Material	trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]cyclohexaneacetic acid
Recommended Storage	Store at 4°C
Molecular Formula	C₂₁H₂₄N₄O₄
Formula Weight	Observed MW: 396.44
Assay Percent Range	>98%

MedChemExpress PF-04620110 is a potent, selective and orally bioavailable diglyceride acyltransferase-1 (DGAT-1) inhibitor with an IC50 of 19 nM.

Molecular Weight (g/mol)	396.44
Color	Off-White
Physical Form	Solid
Chemical Name or Material	PF-04620110
Grade	Research
SMILES	O=C(C[C@@H]1CC[C@H](CC1)C2=CC=C(C=C2)N3CCOC4=NC=NC(N)=C4C3=O)O
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	99.3%
CAS	1109276-89-2
Solubility Information	DMSO : 12.5 mg/mL (31.53 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₂₄N₄O₄
Formula Weight	396.44

Potent and selective DGAT-1 inhibitor; orally bioavailable