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CAS RN 1154-25-2

CAS RN 1154-25-2

IUPAC Name: 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
Synonyms: 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(isopropyl)amino]pyrazine-2-carboxamide
Molecular Weight (g/mol): 299.76
Molecular Formula: C11H18ClN7O
InChi Key: QDERNBXNXJCIQK-UHFFFAOYSA-N
SMILES: CCN(C(C)C)C1=NC(N)=C(N=C1Cl)C(=O)N=C(N)N
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1

EIPA, Tocris Bioscience™

CAS: 1154-25-2 Molecular Formula: C11H18ClN7O Molecular Weight (g/mol): 299.76 MDL Number: MFCD00151710 InChI Key: QDERNBXNXJCIQK-UHFFFAOYSA-N Synonym: eipa,5-n-ethyl-n-isopropyl amiloride,ethylisopropylamiloride,5-ethylisopropyl amiloride,ethyl isopropyl amiloride,unii-vw50ce070t,5-n-ethyl-n-isopropyl-amiloride,3-amino-n-aminoiminomethyl-6-chloro-5-ethyl 1-methylethyl amino-2-pyrazinecarboxamide,n-amidino-3-amino-5-ethylisopropylamino-6-chloropyrazine carboxamide PubChem CID: 1795 IUPAC Name: 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide SMILES: CCN(C(C)C)C1=NC(N)=C(N=C1Cl)C(=O)N=C(N)N

PubChem CID 1795
CAS 1154-25-2
Molecular Weight (g/mol) 299.76
MDL Number MFCD00151710
SMILES CCN(C(C)C)C1=NC(N)=C(N=C1Cl)C(=O)N=C(N)N
Synonym eipa,5-n-ethyl-n-isopropyl amiloride,ethylisopropylamiloride,5-ethylisopropyl amiloride,ethyl isopropyl amiloride,unii-vw50ce070t,5-n-ethyl-n-isopropyl-amiloride,3-amino-n-aminoiminomethyl-6-chloro-5-ethyl 1-methylethyl amino-2-pyrazinecarboxamide,n-amidino-3-amino-5-ethylisopropylamino-6-chloropyrazine carboxamide
IUPAC Name 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
InChI Key QDERNBXNXJCIQK-UHFFFAOYSA-N
Molecular Formula C11H18ClN7O
2

EIPA, MedChemExpress

MedChemExpress EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 299.76
Color Yellow
Physical Form Solid
Chemical Name or Material EIPA
Grade Research
SMILES O=C(C1=NC(Cl)=C(N(CC)C(C)C)N=C1N)NC(N)=N
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 1154-25-2
Solubility Information DMSO : 140 mg/mL (467.04 mM; Need ultrasonic)
Health Hazard 1 H315∣H319∣H335
Synonym L593754 MH 12-43
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C11H18ClN7O
Formula Weight 299.76