CAS RN 1257044-40-8

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Tocris™ ABT 199

Selective, high affinity Bcl-2 inhibitor; orally bioavailable

Pricing and Availability
Specifications

Target	Bcl-2 Family Inhibitors
CAS	1257044-40-8
Product Type	Inhibitor
Purity	98%
Chemical Name or Material	4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2 H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1 H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Recommended Storage	Store at -20°C
Synonym	GDC-0199
Molecular Formula	C₄₅H₅₀ClN₇O₇S
Formula Weight	868.45

Medchem Express Venetoclax, MedChemExpress

MedChemExpress Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	868.44
Color	Yellow
Physical Form	Powder
Chemical Name or Material	Venetoclax
Grade	Research
SMILES	O=C(NS(=O)(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCN(CC5=C(C6=CC=C(Cl)C=C6)CC(C)(C)CC5)CC4)C=C3OC7=CN=C(NC=C8)C8=C7
For Use With (Application)	Cancer-programmed cell death
Percent Purity	95.0%
CAS	1257044-40-8
Solubility Information	DMSO : 77.5 mg/mL (89.24 mM; Need ultrasonic) ∣Ethanol : < 1 mg/mL (insoluble)
Synonym	ABT-199 GDC-0199
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₄₅H₅₀ClN₇O₇S
Formula Weight	868.44

CAS RN 1257044-40-8

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