CAS RN 2361241-23-6
CAS RN 2361241-23-6
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Medchem Express BI-749327, MedChemExpress
MedChemExpress BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7.
