CAS RN 126411-39-0
IUPAC Namn:
diethyl [2-(3,5-di-tert-butyl-4-hydroxyphenyl)-1-(diethoxyphosphoryl)ethenyl]phosphonate
Synonymer:
diethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-1-(diethoxyphosphoryl)ethenylphosphonate
Molekylvikt (g/mol):
504.54
Molekylär sammansättning:
C24H42O7P2
InChi Key:
YQLJDECYQDRSBI-UHFFFAOYSA-N
SMILES:
CCOP(=O)(OCC)C(=CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)P(=O)(OCC)OCC
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Resultat
1
Tocris Bioscience™ SR 12813
CAS: 126411-39-0 Molekylformel: C24H42O7P2
2
SR12813, MedChemExpress
MedChemExpress SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR).