CAS RN 162112-37-0
IUPAC Namn:
N-(3-hydroxypropyl)-5-methyl-1-{4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}-1H-pyrazole-4-carboxamide
Synonymer:
N-(3-hydroxypropyl)-5-methyl-1-{4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}pyrazole-4-carboxamide
Molekylvikt (g/mol):
410.42
Molekylär sammansättning:
C18H17F3N4O2S
InChi Key:
HOFGTYCLOKDAES-UHFFFAOYSA-N
SMILES:
CC1=C(C=NN1C1=NC(=CS1)C1=CC(=CC=C1)C(F)(F)F)C(=O)NCCCO
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Resultat
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RWJ 50271, MedChemExpress
MedChemExpress RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion.
