CAS RN 1782235-14-6

IUPAC Namn: 6-[(2-{[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile trihydrochloride

Synonymer: 6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methyl-3H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile trihydrochloride

Molekylvikt (g/mol): 574.72

Molekylär sammansättning: C22H21Cl5N8

InChi Key: DSFVSCNMMZRCIA-UHFFFAOYSA-N

SMILES: Cl.Cl.Cl.CC1=CN=C(N1)C1=CN=C(NCCNC2=NC=C(C=C2)C#N)N=C1C1=C(Cl)C=C(Cl)C=C1

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CAS: 1782235-14-6 Molekylformel: C22H21Cl5N8

Molekylformel	C22H21Cl5N8
CAS	1782235-14-6

MedChemExpress Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM.

Molekylformel	C₂₂H₂₁Cl₅N₈
Rekommenderad förvaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt	574.72
Hållbarhet	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Hälsofara 1	H302∣H315∣H319∣H335
Löslighetsinformation	DMSO : ≥ 32 mg/mL (55.68 mM) ∣H2O : 19 mg/mL (33.06 mM; Need ultrasonic and warming)
Anteckningar om renhetsgrad	Research
Fysisk form	Powder
Kvalitet	Research
Färg	White
CAS	1782235-14-6
LEDER	N#CC1=CC=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)N=C1.[H]Cl.[H]Cl.[H]Cl
Molekylvikt (g/mol)	574.72
Synonym	CHIR-99021 trihydrochloride CT99021 trihydrochloride
Kemiskt namn eller material	Laduviglusib trihydrochloride
Procent renhet	98.01%
För användning med (applikation)	Cancer-Kinase/protease