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CH3NH3COHNNNHNFClOO(E/Z)

CAS RN 850140-72-6

IUPAC Namn: N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(oxolan-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide
Synonymer: afatinib
Molekylvikt (g/mol): 485.94
Molekylär sammansättning: C24H25ClFN5O3
InChi Key: ULXXDDBFHOBEHA-UHFFFAOYNA-N
SMILES: CN(C)CC=CC(=O)NC1=C(OC2CCOC2)C=C2N=CN=C(NC3=CC(Cl)=C(F)C=C3)C2=C1
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1 – 5 av 5 Resultat
1

Thermo Scientific Chemicals Afatinib

CAS: 850140-72-6 Molekylformel: C24H25ClFN5O3

Molekylformel C24H25ClFN5O3
CAS 850140-72-6
2

Afatinib, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

3

Afatinib, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

4

Afatinib, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

5

Afatinib, MedChemExpress

MedChemExpress Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer.

ENCOMPASS_PREFERRED
Molekylformel C24H25ClFN5O3
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 485.94
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Hälsofara 1 H315∣H319∣H335
Löslighetsinformation DMSO : 100 mg/mL (205.79 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 850140-72-6
LEDER O=C(NC1=C(C=C2C(C(NC3=CC(Cl)=C(C=C3)F)=NC=N2)=C1)O[C@H]4CCOC4)/C=C/CN(C)C.[(E)]
Molekylvikt (g/mol) 485.94
Synonym BIBW 2992
Kemiskt namn eller material Afatinib
Procent renhet 98.0%
För användning med (applikation) Cancer-Kinase/protease