CAS RN 85416-73-5
IUPAC Namn:
(4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
Synonymer:
(+)-rolipram (S)-(+)-rolipram
Molekylvikt (g/mol):
275.35
Molekylär sammansättning:
C16H21NO3
InChi Key:
HJORMJIFDVBMOB-GFCCVEGCSA-N
SMILES:
COC1=CC=C(C=C1OC1CCCC1)[C@H]1CNC(=O)C1
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(S)-(+)-Rolipram, MedChemExpress
MedChemExpress (S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC50 of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells.
