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CAS RN 942183-80-4

IUPAC Namn: 1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide
Synonymer: 1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide
Molekylvikt (g/mol): 587.69
Molekylär sammansättning: C33H33N9O2
InChi Key: HDAJDNHIBCDLQF-UHFFFAOYNA-N
SMILES: O=C(CN1CCC(C1)C(=O)NC1=CC=C2NN=C(C2=C1)C1=CC=NC=C1)N1CCN(CC1)C1=CC=C(C=C1)C1=NC=CC=N1
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SCH772984, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

3

SCH772984, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

4

SCH772984, MedChemExpress

MedChemExpress SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-naïve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations.

ENCOMPASS_PREFERRED
Molekylformel C33H33N9O2
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 587.67
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation DMSO : 48 mg/mL (81.68 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Yellow
CAS 942183-80-4
LEDER O=C([C@H](CC1)CN1CC(N(CC2)CCN2C(C=C3)=CC=C3C4=NC=CC=N4)=O)NC5=CC6=C(C=C5)NN=C6C7=CC=NC=C7
Molekylvikt (g/mol) 587.67
Kemiskt namn eller material SCH772984
Procent renhet 98.69%
För användning med (applikation) Cancer-Kinase/protease