missing translation for 'onlineSavingsMsg'
Learn More

AATF Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10282-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16886563

  • 4721.67 SEK / 150µL
Estimated Shipment: 26-06-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK), a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases. AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal, features which are typical of transcription factors. AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways. Recently, it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the beta-peptide by interacting with Par-4 (prostate apoptosis response-4), another pro-apoptotic leucine zipper protein that is associated with neuronal degeneration in Alzheimer′s disease (AD), suggesting that AATF may have potential therapeutic applications in both familial and sporadic forms of AD.
Specifications

Specifications

AATF
Polyclonal
Unconjugated
AATF
AATF, CHE 1, CHE1, DED, Protein AATF, Rb binding protein Che 1, Traube
Rabbit
Antigen Affinity Chromatography
RUO
114512, 26574, 56321
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Western Blot
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9JKX4, Q9NY61, Q9QYW0
AATF
AATF Fusion Protein Ag0195
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers