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ADRA2B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19778-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16879254

  • 1211.96 SEK / 20µL
Estimated Shipment: 30-11-2021

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Description

Description

The antibody is specific to ADRA2B.

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.
Specifications

Specifications

ADRA2B
0.14 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P18089, P19328, P30545
ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, Alpha 2B adrenergic receptor, Alpha 2B adrenoceptor, Alpha 2B adrenoreceptor, Alpha 2BAR, ALPHA2BAR
Rabbit
IgG
20 μL
-20°C
Primary
11552, 151, 24174
Flow Cytometry, Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
ADRA2B
Liquid
Adra2b
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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