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ALDH2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15310-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16884434

  • 3313.85 SEK / 150µL
Estimated Shipment: 06-12-2021

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Description

Description

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Specifications

Specifications

ALDH2
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P05091, P11884, P47738
ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM
Rabbit
IgG
150 μL
-20°C
Primary
11669, 217, 29539
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
ALDH2
Liquid
ALDH2
ALDH2 Fusion Protein Ag7452
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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