missing translation for 'onlineSavingsMsg'
Learn More

Alpha E catenin Mouse anti-Human, Mouse, Clone: 2B7B8, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66221-1-IG-20UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16887895

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
Specifications

Specifications

Alpha E catenin
Monoclonal
2.08 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P26231, P35221
CTNNA1
Alpha E catenin Fusion Protein Ag23603
20 μL
Primary
Human, Mouse
Antibody
IgG1
Western Blot, Immunohistochemistry (Paraffin)
2B7B8
Unconjugated
CTNNA1
Alpha E catenin, Cadherin associated protein, CAP102, Catenin alpha 1, CTNNA1
Mouse
Protein G
RUO
12385, 1495
-20°C
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers