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CD184 Mouse anti-Human, APC, Clone: 12G5, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 555976
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Beskrivning
Reacts with fusin (CXCR4), a seven-transmembrane domain, G-protein-linked glycoprotein. Fusin is expressed on a wide variety of CD4+ and CD4- cells including those from spleen, brain and lung. It has been shown to function as a cofactor for infection with T-cell tropic strains of HIV-1 and also as a receptor for CD4-independent infection. 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.
Host Species: Mouse
Clone: 12G5
Isotype: IgG2a κ
Species Reactivity: Human
Flow Cytometry
Specifikationer
| CD184 | |
| Monoclonal | |
| APC | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| SIVmac variant CP-MAC-infected Sup-T1 cells | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG2a κ |
| Flow Cytometry | |
| 12G5 | |
| CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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Produkttitel
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