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ARL3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10961-1-AP-20UL

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Product Code. 16887693

  • 1645.54 SEK / 20µL

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Description

Description

ADP-ribosylation factors (ARFs) are low molecular weight GTP-binding proteins belonging to the RAS superfamily. The predicted 182-amino acid ARL3 (ADP-ribosylation like factor) protein shares 97% amino acid identity with rat ARLl3 and 43% identity with human ARF1. Like the ARFs, ARL3 has a glycine at position 2, the site of N myristoylation, and lacks cysteine residues near the C terminus, which are found in other members of the RAS family. Northern blot analysis detected a 1-kb ARL3 transcript in all tissues tested, with highest expression in heart and lung, and lower expression in brain, liver, kidney, ovary, and testis. A 5.5-kb transcript was also detected in most tissues, with highest expression in brain. Immunoblot analysis detected ARL3 in human tumor cell lines but not in normal rodent cells. Although ARL3 binds GTP, it is devoid of activity in the cholera toxin-dependent ADP-ribosylation of Gs, and is therefore classified as an ARF-like protein.
Specifications

Specifications

ARL3
Polyclonal
Unconjugated
ARL3
ADP ribosylation factor like 3, ARFL3, ARL3
Rabbit
Antigen Affinity Chromatography
RUO
403, 56350, 64664
-20°C
Liquid
Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence
0.28 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P36405, P37996, Q9WUL7
Arl3
ARL3 Fusion Protein Ag1406
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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ARL3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 20 μL; Unconjugated

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