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Invitrogen™ Human AURKC (Aurora C), GST Tag Recombinant Protein Product Code.: 10023912
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Invitrogen™ Human AURKC (Aurora C), GST Tag Recombinant Protein

Product Code. 10023912
1 mg, 1mg
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Quantity:
1 mg
10 ÎĽg
Unit Size:
10µg
1mg
This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Product Code. 10023912

Brand: Invitrogen™ PV4178

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This item is not returnable. View return policy

For Research Use Only. All usage must comply with product instructions.

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 ÎĽg, 10 ÎĽg and 20 ÎĽg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 ÎĽL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome/spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9UQB9
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 6795
Molecular Weight (g/mol) 61.7 kDa
Name Human AURKC (Aurora C), GST Tag
Quantity 1 mg
Regulatory Status For research use only. Not for use in diagnostic procedures
Gene Alias AIE1; AIE2; AIK3; AIRK3; ARK3; ARK-3; AurC; AURKC; Aurora 3; aurora B; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; aurora-C; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; SPGF5; STK13
Common Name Aurora C
KinaseFamily Aurora
Product Type AURKC (Aurora C) Recombinant Human Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Insect cells
Form Liquid
Purity or Quality Grade 90% by SDS-PAGE
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