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BAIAP2L1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25692-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16884255

  • 1211.96 SEK / 20µL
Estimated Shipment: 30-11-2021

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Description

Description

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
Specifications

Specifications

BAIAP2L1
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9UHR4
BAIAP2L1, IRTKS
Rabbit
IgG
20 μL
-20°C
Primary
55971
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
BAIAP2L1
Liquid
BAIAP2L1
BAIAP2L1 Fusion Protein Ag22499
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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