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BAIAP2L1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 25692-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.Specifications
BAIAP2L1 | |
Polyclonal | |
Unconjugated | |
BAIAP2L1 | |
BAIAP2L1, IRTKS | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
55971 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.27 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q9UHR4 | |
BAIAP2L1 | |
BAIAP2L1 Fusion Protein Ag22499 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |