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BIN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14647-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.Specifications
BIN1 | |
Polyclonal | |
Unconjugated | |
BIN1 | |
AMPH2, Amphiphysin II, Amphiphysin like protein, AMPHL, BIN1, bridging integrator 1, SH3P9 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
117028, 274, 30948 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.44 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O00499, O08539, O08839 | |
Bin1 | |
BIN1 Fusion Protein Ag6240 | |
20 μL | |
Primary | |
Mouse, Human, Rat | |
Antibody | |
IgG |