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BIN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1236.20 SEK - 3313.85 SEK

Specifications

Antigen BIN1
Concentration 0.44 mg/mL
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16813394
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Proteintech
14647-1-AP-150UL
150 μL
3313.85 SEK
150µL
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Estimated Shipment: 20-05-2022
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16823394
View Documents Promotion Details
Proteintech
14647-1-AP-20UL
20 μL
1236.20 SEK
20µL
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Estimated Shipment: 20-05-2022
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Description

Description

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Specifications

Specifications

BIN1
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Antigen Affinity Chromatography
0.44 mg/mL
Polyclonal
Rabbit
Human, Mouse, Rat
IgG
Antibody
SDS
Product Certifications