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  4. ACROBiosystems Biotinylated Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His, Avitag™&Tag Free

ACROBiosystems Biotinylated Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His, Avitag™&Tag Free

Biotinylated Protein

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POA

Specifications

Accession Number NP 000876.3 (ITGA4) and NP_000880.1 (ITGB7)
Molecular Weight (g/mol) 113.2 kDa (ITGA4) and 81.8 kDa (ITGB7)
Source Biotinylated Human ITGA4&ITGB7; Heterodimer Protein, His,Avitag&Tag; Free (IT7-H82W9) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7) (Accession # P13612-1 (ITGA4) and P26010-1 (ITGB7)).
Immunogen Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7)
Storage Requirements -20°C
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Description

Description

Integrin alpha 4 beta 7 is an integrin family adhesion receptor that shares subunits with alpha 4 beta 1 (VLA4) and the E-Cadherin receptor, alpha E beta 7 . Integrin alpha 4 beta 7, which is critical for homing to intestinal mucosa, is induced during T cell activation in Peyer’s patches or mesenteric lymph nodes.Its expression requires signals from local dendritic and stromal cells, including secreted retinoic acid. The HIV-1 envelope protein gp120 binds to the active form of Integrin alpha 4 beta 7, and this may or may not account for the concentration of HIV-1 virus in the gut-associated lymphoid tissue (GALT). Integrin alpha 4 beta 7 may also be involved in lymphocyte trafficking in acute intestinal graft vs. host disease (GVHD).

Biotinylated Human ITGA4&ITGB7 Heterodimer Protein, His,Avitag&Tag Free, produced by co-expression of ITGA4 and ITGB7, has a calculated MW of 113.2 kDa (ITGA4) and 81.8 kDa (ITGB7). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followed
Specifications

Specifications

NP 000876.3 (ITGA4) and NP_000880.1 (ITGB7)
Biotinylated Human ITGA4&ITGB7; Heterodimer Protein, His,Avitag&Tag; Free (IT7-H82W9) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7) (Accession # P13612-1 (ITGA4) and P26010-1 (ITGB7)).
-20°C
Integrin alpha 4 beta 7
Human
HEK293
MABSol™ Biotin Labeled Proteins
113.2 kDa (ITGA4) and 81.8 kDa (ITGB7)
Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7)
Integrin alpha 4 beta 7,ITGA4andITGB7
Precision Avi
His Tag and Avi Tag
Powder
Videos
SDS
Documents

Documents

Product Certifications
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