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c-Cbl Mouse anti-Human, Clone: 2F6D1, Proteintech

Mouse Monoclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen c-Cbl
Clone 2F6D1
Concentration 1 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16888575
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Proteintech
66576-1-IG-20UL
20 ÎĽL
1645.54 SEK
20µL
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16878575
View Documents
Proteintech
66576-1-IG-150UL
150 ÎĽL
4652.90 SEK
150µL
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Description

Description

Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.
Specifications

Specifications

c-Cbl
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
C CBL, CBL, CBL2, c-Cbl, Proto oncogene c Cbl, RING finger protein 55, RNF55
CBL
IgG1
Protein G
Antibody
2F6D1
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Mouse
Human
P22681
867
c-Cbl Fusion Protein Ag23033
Primary
-20°C
CBL
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SDS
Documents

Documents

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c-Cbl Mouse anti-Human, Clone: 2F6D1, Proteintech

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