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c-Cbl Mouse anti-Human, Clone: 2F6D1, Proteintech
Mouse Monoclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
| Antigen | c-Cbl |
|---|---|
| Clone | 2F6D1 |
| Concentration | 1 mg/mL |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16888575
|
Proteintech
66576-1-IG-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 24-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
16878575
|
Proteintech
66576-1-IG-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 24-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.Specifications
| c-Cbl | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| C CBL, CBL, CBL2, c-Cbl, Proto oncogene c Cbl, RING finger protein 55, RNF55 | |
| CBL | |
| IgG1 | |
| Protein G | |
| Antibody |
| 2F6D1 | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Mouse | |
| Human | |
| P22681 | |
| 867 | |
| c-Cbl Fusion Protein Ag23033 | |
| Primary | |
| -20°C | |
| CBL |