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ErbB3 (HER-3) Monoclonal Antibody (SGP1), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-6555-42

2390.11 SEK valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.23750kg

Product Code. 15559336

  • 3585.00 SEK / 100 tests
Estimated Shipment: 08-05-2024
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Description

Description

Description: This SGP1 monoclonal antibody reacts with human c-ErbB3, which is also known as HER3. This epidermal growth factor (EGF) receptor family member is expressed on normal human tissues, particularly on neurons and cells of the gastrointestinal tract. c-ErbB3 is overexpressed in a variety of cancers, including breast, ovary, and gastrointestinal carcinomas. Upon binding its ligand heregulin beta-1, c-ErbB3 is activated by heterodimerization with ErbB2 or EGFR1. Dependent on PI3K signaling, c-ErbB3 mediates tumor cell invasion, intravasation, and metastasis. Expression of this cell surface receptor has been used as a prognostic marker for breast cancer. The SGP1 antibody has been reported to stimulate anchorage-independent growth of breast cancer cell lines. Applications Reported: This SGP1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This SGP1 antibody has been pre-titrated and tested by flow cytometric analysis of the MCF7 cell line. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. PerCP-eFluor™ 710 can be used in place of PE-Cy5, PE-Cy5.5 or PerCP-Cy5.5. PerCP-eFluor™ 710 emits at 710 nm and is excited with the blue laser (488 nm).

ErbB3 (HER-3) Monoclonal antibody specifically detects ErbB3 (HER-3) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

ErbB3 (HER-3)
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P21860
ERBB3
Affinity chromatography
RUO
2065
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
SGP1
PerCP-eFluor 710
ERBB3
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Mouse
100 Tests
Primary
Human
Antibody
IgG1
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