missing translation for 'onlineSavingsMsg'
Learn More

c-Rel Monoclonal Antibody (1RELAH5), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Invitrogen 14-6111-80

 View more versions of this product

Product Code. 15237707

This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
View alternative products »

This item is not returnable. View return policy

Description

Description

Description: The 1RELAH5 monoclonal antibody reacts with mouse c-Rel. c-Rel is a 65 kDa hematopoietic lineage-restricted member of the NF-kB family of transcription factors. In the thymus, c-Rel is upregulated in regulatory T cells (Treg) when compared to other CD4+ thymocytes. c-Rel is believed to play a critical role in thymic Treg (nTreg) development, but is not necessary for TGF beta-mediated T reg (iTreg) differentiation. C-Rel is also involved in proliferation and survival in mature T cells. Applications Reported: This 1RELAH5 antibody has been reported for use in western blotting. Applications Tested: This 1RELAH5 antibody has been tested by western blot analysis of mouse splenocytes. This can be used at 1-5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA, RELB (604758), NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the ′Rel domain,′ which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (Belguise and Sonenshein, 2007).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

c-Rel
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P15307
Rat
25 μg
Primary
Mouse
Antibody
IgG2a κ
Western Blot
1RELAH5
Unconjugated
Rel
Rel
Affinity chromatography
RUO
19696
4° C
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
c-Rel Monoclonal Antibody (1RELAH5), eBioscience™, Invitrogen™ > 25 μg; Unconjugated

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.

For Research Use Only.