Learn More
C9orf78 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14496-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
The MW of this protein is 34 kDa, and this antibody specifically recognizes the 34 kDa protein. This antibody works well in WB, IHC and IF applications.
MLH1 is a DNA mismatch repair protein. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.Specifications
C9orf78 | |
Polyclonal | |
Unconjugated | |
C9orf78 | |
C9orf78, HCA59, HSPC220 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
311855, 51759 | |
-20°C | |
Liquid |
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry | |
0.28 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q9NZ63 | |
C9orf78, RGD1305178 | |
C9orf78 Fusion Protein Ag5919 | |
150 μL | |
Primary | |
Rat, Mouse, Human | |
Antibody | |
IgG |