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Calnexin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | Calnexin |
---|---|
Concentration | 0.39 mg/mL |
Applications | Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16826813
|
Proteintech
10427-2-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 03-04-2024 Log in to see stock. |
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16816813
|
Proteintech
10427-2-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 03-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Calnexin, also referred to as IP90, p88 and p90, is an approximately 90 kDa integral membrane protein of the endoplasmic reticulum (ER). Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins. Studies indicate that calnexin associates with the major histocompatibility complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes. It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP78 and GRP94 and protein disulfide isomerase. Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention. Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids).Specifications
Calnexin | |
Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry | |
Unconjugated | |
Rabbit | |
Rat, Human, Mouse | |
P27824, P35564, P35565 | |
12330, 29144, 821 | |
Calnexin Fusion Protein Ag0697 | |
Primary | |
-20°C | |
CANX |
0.39 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
calnexin, CANX | |
Canx | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |