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Calsequestrin 2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1C10A1, Proteintech

Mouse Monoclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen Calsequestrin 2
Clone 1C10A1
Concentration 1 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16898275
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Proteintech
66419-1-IG-20UL
20 ÎĽL
1645.54 SEK
20µL
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16888275
View Documents
Proteintech
66419-1-IG-150UL
150 ÎĽL
4652.90 SEK
150µL
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Description

Description

Calsequestrin (CASQ) is a Ca2+-binding protein present primarily in junctional sarcoplasmic reticulum of skeletal and cardiac muscle; the cardiac form (CASQ2) is encoded by a separate gene. The primary role of CASQ2 is buffering of the sarcoplasmic reticulum Ca2+ ions, but another role for CASQ2 has emerged recently: CASQ2 regulates the open probability of ryanodine receptor 2 (RyR2). Mutations in CASQ2 cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
Specifications

Specifications

Calsequestrin 2
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Calsequestrin 2, CASQ2, PDIB2
Casq2
IgG2a
Protein A
Antibody
1C10A1
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Mouse
Human, Pig, Mouse, Rat
O09161, O14958, O18934, P51868
12373, 29209, 397436, 845
Calsequestrin 2 Fusion Protein Ag13246
Primary
-20°C
CASQ2
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SDS
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Documents

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Calsequestrin 2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1C10A1, Proteintech

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