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CBX4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 18544-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16878534

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintece. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
Specifications

Specifications

CBX4
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O00257, O55187
CBX4, Chromobox protein homolog 4, E3 SUMO protein ligase CBX4, hPC2, NBP16, PC2, Polycomb 2 homolog
Rabbit
IgG
20 μL
-20°C
Primary
12418, 501403, 8535
Immunocytochemistry, Western Blot, Immunofluorescence
Unconjugated
CBX4
Liquid
Cbx4
CBX4 Fusion Protein Ag13425
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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